IMPACT OF TISSUE FACTOR EXPRESSION AND ADMINISTRATION ROUTES ON THROMBOSIS DEVELOPMENT INDUCED BY MESENCHYMAL STEM/STROMAL CELL INFUSIONS: RE-EVALUATING THE DOGMA

Abstract Background Hyperactive coagulation might cause dangerous complications such as portal vein thrombosis and pulmonary embolism after mesenchymal stem/stromal cell (MSC) therapy.Tissue factor (TF), an initiator of the extrinsic coagulation pathway, has been suggested as a predictor of this process.Methods The expression of TF and other pro- a

Abstract The release of domesticated conspecifics into the natural environment, whether deliberate or accidental, has the potential to alter the genetic integrity and evolutionary trajectory of wild populations.This widespread challenge is of particular concern for wild Atlantic salmon.By investigating phenotypic differences between the offspring o